RapiZyme Cusativin is a recombinant endonuclease designed for advanced digestion and characterization of RNA, including mRNA and sgRNA, prior to LC-MS analysis. It is provided as a lyophilized bead in a skirted tube with LC-MS compatible additives to improve stability and maintain high activity upon reconstitution, and primarily targets 3' Cytidine cleavage for improved sequence coverage.
- Recombinant endonuclease for advanced RNA digestion and characterization.
- Supplied as a lyophilized bead in a skirted tube.
- Contains LC-MS compatible additives for enhanced stability and activity.
- Primarily targets 3' cytidine cleavage, yielding longer RNA digestion products.
- Robust and automation-friendly procedure.
- Supports identity, purity, and critical quality attribute testing of RNA therapeutics.
- Enables comprehensive sequence mapping and orthogonal oligonucleotide LC-MS maps.